Platelet Rich Plasma

Platelet rich plasma (PRP) is substance that is a by-product of blood (plasma) that is rich in platelets. Until now, its use has been confined to the hospital setting. New technology permits the doctor to harvest and produce a sufficient quantity of platelets from only 20 cc of blood drawn from the patient while they are having outpatient surgery.

PRP permits the body to take advantage of the normal healing pathways at a greatly accelerated rate. During the healing process, the body rushes many cells and cell-types to the wound in order to initiate the healing process. One of those cell types is platelets. Platelets perform many functions, including formation of a blood clot and release of growth factors (GF) into the wound. These GF (platelet derived growth factors PGDF, transforming growth factor beta TGF, and insulin-like growth factor ILGF) function to assist the body in repairing itself by stimulating stem cells to regenerate new tissue. The more growth factors released and sequestered into the wound, the more stem cells stimulated to produce new host tissue. Thus, one can easily see that PRP permits the body to heal faster and more efficiently.

A subfamily of TGF is bone morphogenic protein (BMP). BMP has been shown to induce the formation of new. This is of great significance to the surgeon who places dental implants. By adding PRP, and thus BMP, to the implant site with bone substitute particles, the implant surgeon can now grow bone more predictably and faster than ever before.

PRP Has Many Clinical Applications

PRP is used for bone grafting for dental implants; on-lay and in-lay grafts; sinus lift procedures, ridge augmentation procedures, and closure of cleft, lip, and palate defects. Repair of bone defects creating by removal of teeth or small cysts. Repair of fistulas between the sinus cavity and mouth.

PRP Has Many Advantages

  • Safety: PRP is a by-product of the patient’s own blood therefore the question of disease transmission is not an issue.
  • Convenience: PRP can be generated in the doctor’s office while the patient is undergoing an outpatient surgical procedure.
  • Faster healing: The supersaturation of the wound with PRP produces an increase of tissue synthesis and thus faster tissue regeneration.
  • Is PRP safe? Yes. During the outpatient surgical procedure a small amount of your own blood is drawn out via the IV. This blood is then placed in the PRP centrifuge machine and spun down. In less than 15 minutes, the PRP is formed and ready to use.